منابع مشابه
Inflammatory myopathies associated with anti-mitochondrial antibodies.
Anti-mitochondrial antibodies, the characteristic markers of primary biliary cirrhosis, have been detected in most patients with this disease. However, the prevalence of these antibodies in inflammatory myopathies and their clinical and histopathological significance has not been determined. Sera from 212 consecutive patients with inflammatory myopathies were screened for anti-mitochondrial ant...
متن کاملAnti– -enolase Antibodies in Patients with Inflammatory Bowel Disease
METHODS: We used a classic proteomic approach with extracts from granulocytes and pANCA-positive ulcerative colitis (UC) sera to confirm -enolase as a target antigen. By means of Western blot analysis, we screened a cohort of 525 subjects for the presence of anti– -enolase antibodies. We performed GeneArray experiments on RNA extracted from colonic mucosal biopsies from 35 IBD and 6 control pat...
متن کاملNodopathy: chronic inflammatory demyelinating polyneuropathy with anti-neurofascin 155 antibodies.
Journal of Neurology Neurosurgery & Psychiatry (ISSN No: 0022-3050) is published monthly by BMJ Publishing Group and is distributed in the USA by Air Business Ltd. Periodicals postage paid at Jamaica NY 11431 POSTMASTER: send address changes to Journal of Neurology Neurosurgery & Psychiatry, Air Business Ltd, c/o Worldnet Shipping Inc., 156-15, 146th Avenue, 2nd Floor, Jamaica, NY 11434, USA. T...
متن کاملAnti-calreticulin antibodies in patients with inflammatory bowel disease.
PURPOSE Although the pathogenesis of inflammatory bowel disease (IBD) is unclear, autoimmune processes seem to play roles in IBD because several types of autoantibodies have been found in it. Calreticulin (CRT) is a soluble Ca2+ binding protein which is present in a wide variety of cells. CRT is localized mainly in the endoplasmic reticulum and is often a target for autoantibodies. The aim of t...
متن کاملAnti-Saccharomyces cerevisiae antibodies in twins with inflammatory bowel disease.
BACKGROUND AND AIMS An increased occurrence of anti-Saccharomyces cerevisiae antibodies (ASCA) is reported in unaffected members of families with Crohn's disease. Whether ASCA is a familial trait due to genetic factors or is caused by exposure to environmental factors is unknown. To assess the genetic influence of ASCA we studied its occurrence in a twin population. PATIENTS AND METHODS ASCA ...
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ژورنال
عنوان ژورنال: Nature Biotechnology
سال: 1999
ISSN: 1087-0156,1546-1696
DOI: 10.1038/10825